Researchers of North Carolina-based Wake Forest Baptist Medical Centre studied 100 men and women who were 53 years or older and suffered from untreated high blood pressure and no other major diseases. Tests were conducted to indicate whether it was the patient's heart or blood vessels that were causing the hypertension.
They found 30 to 40% more vascular disease in women compared to men for the same level of elevated blood pressure. Moreover, they found significant physiologic differences in the women's cardiovascular system, including types and levels of hormones involved in blood pressure regulation, that added to severity and frequency of heart disease.
The number of deaths due to heart diseases significantly dipped in the US in the last two decades among men. However, in the same time, heart disease emerged as the leading cause of death among women. This gender divide prompted the researchers to take up the study.
"Our study findings suggest a need to better understand the female sex-specific underpinnings of the hypertensive processes to tailor optimal treatments for this vulnerable population," said lead author Carlos Ferrario. "We need to evaluate new protocols - what drugs, in what combination and in what dosage - to treat women with high blood pressure," said a press release put out by the university.
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