Countries differ widely on statin use

MUMBAI: The first question that any patient newly diagnosed with high levels of cholesterol would ask is whether he should take statins. After all, doctors across the world consider statins to be the best bet against cholesterol buildup. But there is no uniformity across the world on when should patients be put on a daily dose of statins.

In fact, a study from the Netherlands found that both European and American guidelines overestimated the risk of untoward cardiovascular risk.

The study also found that proportions of individuals eligible for statins differed substantially, with one US guideline recommending statins for nearly all men and two-thirds of women. The study has been released online in the Journal of American Medical Association.

Maryam Kavousi of Erasmus MC-University Medical Center, Rotterdam, looked at the cardiovascular disease (CVD) prevention guidelines developed by the American National Cholesterol Education Program expert panel, the American College of Cardiology/American Heart Association (ACC/AHA) task force and the European Society of Cardiology (ESC).

Around 4,800 Dutch participants who were 55 years of age or older were enlisted for the study. If the American College of Cardiology/American Heart Association guidelines were used, 96.4 % of men and 65.8 % of women were eligible for treatment. As per the American cholesterol education guideline, the portion was 52 % of men and 35.5 % of women while the European guideline recommendation was for 66.1 % of men and 39.1 % of women.

Using the American College of Cardiology approach, average predicted risk versus observed heart events was 21.5 % versus 12.7 % for men and 11.6 % versus 7.9 % for women. Similar overestimation occurred with other models as well.

The Rotterdam concluded there is an urgent need to improve risk predictions to facilitate better decision making by doctors.

Anda sedang membaca artikel tentang

Countries differ widely on statin use

Dengan url

http://obecedes.blogspot.com/2014/03/countries-differ-widely-on-statin-use.html

Anda boleh menyebar luaskannya atau mengcopy paste-nya

Countries differ widely on statin use

namun jangan lupa untuk meletakkan link

Countries differ widely on statin use

sebagai sumbernya